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Summer eczema (insect allergy) in horses

Summer eczema in horses: causes, proven treatment options and when a vet is needed.

Reasonable evidenceOne or a few sound studies in the target species, but still limited or not independently replicated. Further research may change the conclusion.
Published: Last updated: Next review: 27 June 20272 min read

Short & honest

Summer eczema is a genetically determined insect allergy with no cure; insect avoidance remains the cornerstone and allergen-specific immunotherapy shows the strongest clinical evidence (grade B).

Veterinary review not yet completed

This page is awaiting review by a registered veterinary surgeon. Until then, treat the text as education based on the sources listed — not as a verified veterinary judgement.

What is summer eczema?

Summer eczema — medically insect bite hypersensitivity (IBH) — is the most common chronic allergic skin condition in horses worldwide. The prevalence is 5–18%; in Friesians this rises to approximately 18% [1][3]. It is not an infection but an IgE-mediated hypersensitivity reaction to salivary proteins of Culicoides midges (knuts). The predisposition is strongly genetically determined and the condition is incurable — only manageable.

Characteristic symptoms are intense itching, hair loss, crusty or wet patches (often on manes, tail root, belly line and ears) and skin damage caused by scratching. The restlessness associated with this has a measurable impact on the horse's behaviour and movement activity [3].


Approach: what works?

Insect avoidance (core approach, essential)

Maximum avoidance of Culicoides midges is the basis of every treatment plan:

  • Stabling at dusk and dawn, the peak hours of Culicoides activity
  • Fine-mesh eczema rug that covers the body as completely as possible
  • Insect repellents to supplement physical measures

Without adequate insect avoidance, all other measures have less effect.

Allergen-specific immunotherapy (AIT)

AIT with recombinant Culicoides allergens in adjuvant is currently the best-supported treatment option. In a double-blind placebo-controlled trial, 67% of treated horses achieved an improvement of >50% in lesion score in year 1, rising to 89% in year 2 (versus 14% placebo) [1]. An earlier double-blind study confirms the principle [2]. AIT requires consistent, long-term use and does not work equally quickly in every horse.

Corticosteroids

Dexamethasone and prednisolone provide short-term symptom relief and can be used as a course during acute periods. However, repeated or long-term systemic use carries real risks of adverse effects, including an increased risk of laminitis. This medication belongs under the supervision of a veterinary surgeon, not as an independent long-term approach.

Additional options: limited evidence

OptionWhat does the evidence say?
Omega-3 supplementation (e.g. linseed)Widely applied; controlled clinical evidence in horses with IBH is lacking
AntihistaminesUsed in practice; effect in horses is not well demonstrated in trials

For both: they are not harmful when used correctly, but do not expect them to replace insect avoidance or AIT.


Breeding

Because the genetic component is strong, it is recommended not to breed affected animals. This significantly reduces the chance of transmitting the predisposition to offspring [1][3].


When to see a veterinary surgeon?

  • For initial diagnosis: confirmation and drawing up an individual management plan
  • When considering AIT: referral to a specialist for allergen testing
  • If infection is suspected, in case of severe lesions or insufficient response to existing policy
  • Corticosteroids always via the veterinary surgeon, never long-term without supervision

Additional measures are an addition to, never a replacement for, veterinary supervision and proven insect avoidance.

Why this verdict?

Grade B (moderate evidence): several controlled trials are available for allergen-specific immunotherapy, including a double-blind placebo-controlled study from 2024 using recombinant Culicoides allergens [1] and an earlier double-blind study from 1990 [2]. Evidence for adjunctive options such as omega-3 and antihistamines is largely lacking in controlled trials, which lowers the grade.

How we grade evidence →

Legal status (Netherlands)

In the Netherlands, allergen-specific immunotherapy falls under prescription-only veterinary treatment and is only available via a veterinary surgeon.

Sources

  1. [1] Allergen immunotherapy using recombinant Culicoides allergens improves clinical signs of equine insect bite hypersensitivity. Frontiers in Allergy, 2024. RCT doi:10.3389/falgy.2024.1467245
  2. [2] Specific immunotherapy in the treatment of Culicoides hypersensitive horses: a double-blind study. PubMed / Equine Veterinary Journal, 1990. RCT source ↗
  3. [3] The Effect of Insect Bite Hypersensitivity on Movement Activity and Behaviour of the Horse. PMC / Animals (Basel), 2023. Narrative review source ↗

Written by Redactie Diernatuur Wiki

Independent editorial team

An independent editorial team that gathers the literature, grades the evidence and writes according to the editorial charter. Sells nothing and has no commercial interests.

  • Works to a GRADE-style evidence rating
  • No commercial interests